Family Medicine - Clinical Pharmacology News & Articles

MDLinx Family Medicine stands out from other primary care literature review services because of our dedication to keeping our members current in less time. On a daily basis, receive an email with just the 'headlines' covering everything important that published in your specialty in the past 24 hours. Or, choose to Focus On the top articles published in the hottest topics in primary care, such as heart failure, depression, diabetes mellitus, eczema/psoriasis, infectious diseases, rheumatoid arthritis, COPD, General Family Medicine News and many more.

Additional bonus content is also available on this page, including clinical pearls from The Smartest Family Physician, a daily quiz competition from the editors of MDLinx Internal Medicine in collaboration with the Cleveland Clinic Center for Continuing Education. Additionally, enjoy the can’t-miss articles highlighted by our own physician editor, D. Scott Cunningham, MD, PhD.

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Articles

Latest (25) Full Text Articles (829) Focus on Neurologic Disorders

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

141 Long-term effects of alogliptin benzoate in hemodialysis patients with diabetes: a 2-year study Nephron Clinical Practice, June 12, 2013 Clinical Article

142 A meta-analysis of adjuvant therapy after potentially curative treatment for hepatocellular carcinoma Canadian Journal of Gastroenterology, June 12, 2013 Clinical Article

143 Long-term effects of doxazosin, finasteride and combination therapy on quality of life in men with benign prostatic hyperplasia The Journal of Urology, June 12, 2013 Clinical Article

144 Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and meta-analysis The American Journal of Gastroenterology, June 12, 2013 Clinical Article

145 Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques Circulation, June 12, 2013 Clinical Article

146 Cilostazol reduces angiographic restenosis after endovascular therapy for femoropopliteal lesions in the sufficient treatment of peripheral intervention by cilostazol study Circulation, June 12, 2013 Clinical Article

147 Effect of aspirin and antiplatelet drugs on the outcome of the fecal immunochemical test Mayo Clinic Proceedings, June 12, 2013 Evidence Based Medicine Clinical Article

148 Long-term clinical follow-up of the multicentre, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, June 12, 2013 Clinical Article

149 Major bleeding risk in anticoagulated patients receiving concomitant antiplatelet therapy: A prospective study Thrombosis Research, June 12, 2013 Evidence Based Medicine Clinical Article

150 Boceprevir versus placebo with pegylated interferon alfa-2b and ribavirin for treatment of hepatitis C virus genotype 1 in patients with HIV: a randomised, double-blind, controlled phase 2 trial The Lancet Infectious Diseases, June 12, 2013 Clinical Article

151 A randomized, double-blind, placebo-controlled study to assess QTc interval prolongation of standard dose aflibercept in cancer patients treated with docetaxel Journal of Cardiovascular Pharmacology, June 12, 2013 Clinical Article

152 Extended-infusion cefepime reduces mortality in patients with pseudomonas aeruginosa infections Antimicrobial Agents and Chemotherapy, June 12, 2013 Clinical Article

153 Telbivudine plus adefovir therapy for chronic hepatitis B patients with virological breakthrough or genotypic resistance to telbivudine European Journal of Gastroenterology & Hepatology, June 12, 2013 Clinical Article

154 Tocilizumab: A novel humanized anti-interleukin 6 (IL-6) receptor antibody for the treatment of patients with non-RA systemic, inflammatory rheumatic diseases Annals of Medicine, June 12, 2013 Review Article Clinical Article

155 Optimization and qualification of a memory B-cell ELISpot for the detection of vaccine-induced memory responses in HIV vaccine trials Journal of Immunological Methods, June 12, 2013 Clinical Article

156 Estimated glomerular filtration rate is associated with major bleeding complications but not thromboembolic events, in anticoagulated patients taking warfarin Thrombosis Research, June 12, 2013 Evidence Based Medicine Clinical Article

157 Renal sympathetic denervation versus antiarrhythmic drugs for drug-resistant hypertension and symptomatic atrial fibrillation (RSDforAF) trial: study protocol for a randomized controlled trial Full Text Trials, June 12, 2013

158 Correlation of pharmacokinetic/pharmacodynamic-derived predictions of antibiotic efficacy with clinical outcomes in severely ill patients with pseudomonas aeruginosa pneumonia Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, June 12, 2013 Clinical Article

159 Minimizing time to treatment: targeted strategies to minimize time to thrombolysis for acute ischaemic stroke Internal Medicine Journal, June 12, 2013 Clinical Article

160 Epidemiology, prognosis, and treatment of resistant hypertension Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, June 11, 2013 Review Article

50 available pages First Previous 8 9 10 11 12 13 14 15 16 17 Next Last

Clinical Pearls in Family Medicine

No relations were found between abdominal adipose tissue and bone mass, fat mass, blood pressure or triglyceride level in overweight adolescents
According to the Cleveland Clinic, the primary risk factors for coronary artery disease (CAD) are diabetes mellitus, family history, hypertension, hyperlipidemia, tobacco use and male gender
Untreated nocturnal gastroesophageal reflux has been demonstrated to be strongly associated with both respiratory and obstructive sleep apnea symptoms as well as airflow obstruction

» Test your knowledge. Take the Smartest Doc challenge today!

Highlights in Family Medicine

Vitamin D supplementation decreases systemic inflammation in T2DM

In a 12-week randomized, controlled trial, ingestion of a vitamin D-fortified yogurt (170 mg calcium + 500 IU vitamin D/250 mL; n=50) twice daily decreased markers of inflammation compared with placebo yogurt (170 mg calcium; n=50). Compared with baseline measures, the 25(OH)D levels were increased and the TNF-alpha, IL-6, hsCRP, SAA, and IL-10 levels were decreased in the group supplemented with vitamin D compared with the group that received placebo.

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Mediterranean diet associated with decreased diabetes, cardiovascular events, and all-cause mortality

Researchers at the University of Palermo conducted a study involving 9109 subjects with a mean follow-up of 6.2 years which showed that the subjects who adhered to a Mediterranean diet had increased dietary fiber, decreased total dietary fat, and an increased intake of monosaturated-to-saturated fats. Further, the incidence of diabetes, cardiovascular events, and all-cause mortality was lower in the subjects who followed a Mediterranean diet.

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Natalizumab superior to IFN-? 1a in MS patients

Based on a retrospective study conducted at the Federico II University (Naples), researchers have concluded that treatment of patients (n=84) with relapsing-remitting MS natalizumab for 12-24 months resulted in a greater reduction in disease activity (annualized relapse rate, .24 vs. .55, respectively) and disability progression than patients treated with INF-? 1a. The number of contrast-enhancing lesions was also less in the natalizumab-treated group.

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Most Popular Family Med Articles

Last month's top read Top Articles of 2012

1 Nonsteroidal anti-inflammatory drug use, chronic liver disease, and hepatocellular carcinoma Hepatology, May 23, 2013

2 The Immunomodulatory Effects Of Statins In Community-Acquired Pneumonia: A Systematic Review Journal of Infection, May 10, 2013 Evidence Based Medicine Review Article

3 Prescription Opioids for Back Pain and Use of Medications for Erectile Dysfunction Spine, May 17, 2013 Evidence Based Medicine

4 Simvastatin impairs exercise training adaptations JACC - Journal of the American College of Cardiology, April 30, 2013

5 Seizures and antiepileptic drugs in patients with spontaneous intracerebral hemorrhages Seizure - European Journal of Epilepsy, May 3, 2013

6 Hemorrhagic and Ischemic Outcomes After Bivalirudin Versus Unfractionated Heparin During Carotid Artery Stenting Circulation: Cardiovascular Interventions, May 3, 2013

7 Impact of diabetes on treatment outcomes and long-term survival in multidrug-resistant tuberculosis Respiration, May 8, 2013

8 Levomepromazine for nausea and vomiting in palliative care Cochrane Reviews, May 13, 2013 Evidence Based Medicine

9 Spinal Injection Therapy for Low Back Pain JAMA, May 17, 2013

10 Low-dose propranolol and exercise capacity in postural tachycardia syndrome: A randomized study Neurology, May 13, 2013

11 New Oral Anticoagulants in Non-Valvular Atrial Fibrillation High Blood Pressure & Cardiovascular Prevention, May 13, 2013

12 Effects of rosuvastatin versus atorvastatin on small dense low-density lipoprotein: a meta-analysis of randomized trials Heart and Vessels, May 8, 2013 Evidence Based Medicine Review Article

13 Resistant hypertension: a practical clinical approach Journal of Human Hypertension, May 10, 2013

14 Effect of a Novel Calcium Channel Blocker on Abnormal Nocturnal Blood Pressure in Hypertensive Patients The Journal of Clinical Hypertension, May 13, 2013

15 Gender and racial disparities in adherence to statin therapy: A meta-analysis American Heart Journal, April 30, 2013 Evidence Based Medicine Review Article

16 Non-steroidal anti-inflammatory drug hypersensitivity in adults and the factors associated with asthma Respiratory Medicine, May 3, 2013

17 Tolerability of diclofenac sodium 1% gel with concomitant medications known to interact with diclofenac Therapeutics and Clinical Risk Management, May 3, 2013 Free full text

18 Genetics of HDL-C: A Causal Link to Atherosclerosis? Current Atherosclerosis Reports, April 25, 2013 Review Article

19 Diabetes and bone health Maturitas, April 30, 2013

20 Maternal plasma 25-hydroxyvitamin D levels, angiogenic factors, and preeclampsia American Journal of Obstetrics and Gynecology, April 29, 2013

Indexed Journals in Family Medicine: American Family Physician, Archives of Family Med, Annals of Family Med more

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Family Medicine - Clinical Pharmacology News & Articles

Articles

Clinical Pearls in Family Medicine

Highlights in Family Medicine

Vitamin D supplementation decreases systemic inflammation in T2DM

Mediterranean diet associated with decreased diabetes, cardiovascular events, and all-cause mortality

Natalizumab superior to IFN-? 1a in MS patients

Most Popular Family Med Articles

Other Topics in Family Medicine