1The effectiveness of cognitive behavioral therapy with respect to psychological symptoms and recovering autobiographical memory in patients suffering from post-traumatic stress disorderNeuropsychiatric Disease and Treatment  Full Text  Clinical Article
2Tadalafil 5 mg once daily for the treatment of Asian men with lower urinary tract symptoms secondary to benign prostatic hyperplasia: Analyses of data pooled from three randomized, double-blind, placebo-controlled studiesInternational Journal of Urology  Clinical Article
3Mindfulness-based cognitive therapy for depression, current episodes, and prevention of relapseAmerican Journal of Lifestyle Medicine  Clinical Article
4Treatment of postnatal depression with cognitive behavioural therapy, sertraline and combination therapy: A randomised controlled trialAustralian and New Zealand Journal of Psychiatry  Clinical Article
5Depressive symptoms and biomarkers of Alzheimer's disease in cognitively normal older adultsJournal of Alzheimer’s Disease  Clinical Article
6A genetically informed study of the longitudinal relation between irritability and anxious/depressed symptomsJournal of the American Academy of Child & Adolescent Psychiatry  Clinical Article
7Prostate-specific antigen level, stage or Gleason score: Which is best for predicting outcomes after radical prostatectomy, and does it vary by the outcome being measured? Results from Shared Equal Access Regional Cancer Hospital databaseInternational Journal of Urology  Clinical Article
8Association between regular aspirin use and circulating markers of inflammation: a study within the prostate, lung, colorectal and ovarian cancer screening trialCancer Epidemiology, Biomarkers & Prevention  Clinical Article
9Racial variation in prostate cancer upgrading and upstaging among men with low-risk clinical characteristicsEuropean Urology  Full Text  Clinical Article
10A randomized controlled effectiveness trial for PSA screening decision support interventions in two primary care settingsJournal of General Internal Medicine  Clinical Article
1NYU study identifies teens at-risk for synthetic marijuana useNew York University News
2First report of its kind examines the burden of mental illness and addictions on Ontario children and youthCentre for Addiction and Mental Health News
3Joslin scientists find direct link between insulin resistance in the brain and behavioral disordersJoslin Diabetes Center News
4Low sugar uptake in brain appears to exacerbate Alzheimer’sUniversity of Southern California Health News
5Medicare slowdown at riskDartmouth-Hitchcock
6In the short run, a high-fat diet may help minimize heart attack damageLoyola University Health System
7‘Feeding and fasting’ hormone adropin can improve insulin actionSaint Louis University Health News
8Episodes of intense anger associated with high risk of heart attack within the next two hoursEuropean Society of Cardiology News
9Appropriate use of aspirin for heart health evaluatedBaylor College of Medicine News
10Genetics at the heart of cardiovascular healthBaylor College of Medicine News

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Visceral adipose tissue predicts subclinical carotid atherosclerosis

As reported in Ultrasound in Medicine and Biology, ultrasound measurement of visceral adipose tissue, unlike the waist circumference, is associated with ultrasound-measured carotid intima-media thickness and an independent predictor of carotid plaques.

CT screening for lung cancer in patients 55-80 years of age beneficial

As reported in the Annals of Internal Medicine, annual CT screening of ever-smokers between 55 and 80 years of age for lung cancer is beneficial. Such screening would result in 45-54% of diagnoses in stage I or II, a 14% reduction in lung cancer mortality, and 497 deaths averted.

Tobacco and alcohol use significantly increase risk for ESCC

Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.

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Clinical Pearls

Clinical Pearl from Smartest DocIndividuelle und umweltbedingte Faktoren erhöhen unabhängig von der Versorgungsqualität das Risiko für ventilatorassoziierte Pneumonien.

Clinical Pearl from Smartest DocIV valproate is less efficacious than other treatment options for acute migraine in the ED.

Clinical Pearl from Smartest DocHohe Vitamin-C- und Vitamin-E-Spiegel schützen nicht vor Gonarthrose.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List