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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): An open-label, randomised, phase 3 factorial trial The Lancet Oncology, August 22, 2014    Clinical Article

2 Impact of prostatic apical shape and protrusion on early recovery of continence after robot-assisted radical prostatectomy Urology, August 22, 2014    Clinical Article

3 Clinical use of abiraterone in the treatment of metastatic castration-resistant prostate cancer Full Text Research and Reports in Urology, August 22, 2014    Review Article

4 Bone complications among prostate cancer survivors: Long-term follow-up from the prostate cancer outcomes study Prostate Cancer & Prostatic Diseases, August 22, 2014    Clinical Article

5 The expression of glucocorticoid receptor is negatively regulated by active androgen receptor signaling in prostate tumors International Journal of Cancer, August 22, 2014    Clinical Article

6 Extraprostatic extension of prostatic carcinoma: Is its proximity to surgical margin or gleason score important? BJU International, August 22, 2014    Clinical Article

7 Detrusor overactivity does not predict bothersome storage symptoms after photoselective vaporization of the prostate with lithium triborate laser Urology, August 22, 2014    Clinical Article

8 Prostate cancer mortality outcomes and patterns of primary treatment for Aboriginal men in New South Wales, Australia BJU International, August 22, 2014    Clinical Article

9 Effects of a six-month walking intervention on depression in inactive post-menopausal women: A randomized controlled trial Aging and Mental Health, August 22, 2014    Clinical Article

10 High prevalence of vitamin D deficiency and insufficiency in adolescent inpatients diagnosed with eating disorders International Journal of Eating Disorders, August 22, 2014    Clinical Article

11 Thyroid stimulating hormone and serum, plasma, and platelet brain-derived neurotrophic factor during a 3-month follow-up in patients with major depressive disorder Journal of Affective Disorders, August 22, 2014    Clinical Article

12 The effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: A randomized controlled trial Journal of Child Psychology and Psychiatry, August 22, 2014    Clinical Article

13 Alcohol use, anxiety, and insomnia in older adults with generalized anxiety disorder The American Journal of Geriatric Psychiatry, August 22, 2014    Clinical Article

14 Personality as a predictor of depression symptoms in burn patients: A follow-up study Burns, August 22, 2014    Clinical Article

15 Patient satisfaction and adherence to antidepressants Full Text Neuropsychiatric Disease and Treatment, August 22, 2014    Clinical Article

16 The significance of mixed states in depression and mania Current Psychiatry Reports, August 22, 2014    Clinical Article

17 Collective efficacy and depressive symptoms in Brazilian elderly Archives of Gerontology and Geriatrics, August 22, 2014    Clinical Article

18 The Spanish version of the Quick Inventory of Depressive Symptomatology–Self Report (QIDS-SR16): A psychometric analysis in a clinical sample Journal of Affective Disorders, August 22, 2014    Clinical Article

19 Aripiprazole once-monthly for treatment of schizophrenia: Double-blind, randomised, non-inferiority study The British Journal of Psychiatry, August 22, 2014    Clinical Article

20 Effects of psychotherapy on DNA strand break accumulation originating from traumatic stress Psychotherapy and Psychosomatics, August 22, 2014    Clinical Article

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Highlights in Family Medicine

s-H-FABP levels predict outcome in ICU patients

As reported in Clinical Research in Cardiology, the level of serum heart-type fatty acid-binding protein (s-H-FABP) is higher in ER patients admitted to the ICU than ER patients admitted to other departments. The s-H-FABP level was also higher in ICU non-survivors than ICU survivors. A s-H-FABP level of 20.95 ng/ml had a 81.1% and 66.0% sensitivity and specificity, respectively, for in-hospital mortality.

Combination tiotropium + formoterol superior to tiotropium alone in COPD patients

As reported in Pulmonary Pharmacology & Therapeutics, combination tiotropium (18 mcg) + formoterol (12 mcg) was superior to tiotropium alone in COPD (n=44) patients inadequately controlled with bronchodilator monotherapy. Combination therapy resulted in an increased bronchodilator response (FEV1 and FVC) and a maximum change in FEV1 and FVC over 24 h.

Green tea reduces BP and improves lipid profile

As reported in Nutrition, Metabolism, and Cardiovascular Diseases, a meta-analysis involved 20 RCTs and 1536 participants showed that consumption of green tea (Camellia sinensis) is associated with a reduction in systolic blood pressure (-1.94 mmHg) and improved lipid profile (TC, -0.13 mmol/l; LDL-C, -0.19 mmol/l). Additional studies quantifying the association are needed.

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