The Latest Clinical Articles in Family Medicine & Family Practice

1Prevention of bone metastases in patients with high-risk nonmetastatic prostate cancer treated with zoledronic acid: Efficacy and safety results of the Zometa European study (ZEUS)European Urology, April 01, 2015  Full Text  Clinical Article
2Comparison of field-of-view (FOV) optimized and constrained undistorted single-shot (FOCUS) with conventional DWI for the evaluation of prostate cancerClinical Imaging, April 01, 2015  Clinical Article
3Magnetic resonance imaging–transectal ultrasound image-fusion biopsies accurately characterize the index tumor: Correlation with step-sectioned radical prostatectomy specimens in 135 patientsEuropean Urology, April 01, 2015  Full Text  Clinical Article
4Symptoms, unmet needs, psychological well-being and health status in prostate cancer survivors: Implications for redesigning follow-upBJU International, April 01, 2015  Clinical Article
5Prevalence of anxiety symptoms and depression in the third gestational trimesterArchives of Gynecology and Obstetrics, April 01, 2015  Clinical Article
6Effects of an integrated stress management program (ISMP) for psychologically distressed students: A randomized controlled trialPerspectives in Psychiatric Care, April 01, 2015  Clinical Article
7Dose painting to treat single-lobe prostate cancer with hypofractionated high-dose radiation using targeted external beam radiation: Is it feasible?Medical Dosimetry, April 01, 2015  Clinical Article
8Enzalutamide: Targeting the androgen signalling pathway in metastatic castration-resistant prostate cancerBJU International, April 01, 2015  Clinical Article
9High sensitivity C reactive protein, fibrinogen levels and the onset of major depressive disorder in post-acute coronary syndromeBMC Cardiovascular Disorders, April 01, 2015  Full Text  Clinical Article
10Baseline characteristic of patients presenting with lacunar stroke and cerebral small vessel disease may predict future development of depressionInternational Journal of Geriatric Psychiatry, April 01, 2015  Clinical Article
1Necklace and smartphone app developed at UCLA can help people track food intakeUCLA Health System, April 01, 2015
2Are antipsychotic drugs more dangerous to dementia patients than we think?University of Michigan Health System, April 01, 2015
3Eat your veggies to lower colon cancer riskBaylor Health Care System, April 01, 2015
4Australians need more calciumInternational Osteoporosis Foundation News, April 01, 2015
5Is painful knee and hand osteoarthritis in middle-aged women associated with excess mortality?International Osteoporosis Foundation News, April 01, 2015
6More than 25 percent of acne patients fail to get prescribed medicationsWake Forest Baptist Medical Center News, April 01, 2015
7Exercise linked to improved erectile and sexual function in menCedars-Sinai, April 01, 2015
8Mayo Clinic study first to identify spontaneous coronary artery disease as inheritedMayo Clinic, April 01, 2015
9Study of brain networks shows why children with obsessive-compulsive disorder might not be able to 'move on'Wayne State University School of Medicine News, April 01, 2015
10Promoting maternal interaction improves growth, weight gain in preemiesNIH News, April 01, 2015

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s-H-FABP levels predict outcome in ICU patients

As reported in Clinical Research in Cardiology, the level of serum heart-type fatty acid-binding protein (s-H-FABP) is higher in ER patients admitted to the ICU than ER patients admitted to other departments. The s-H-FABP level was also higher in ICU non-survivors than ICU survivors. A s-H-FABP level of 20.95 ng/ml had a 81.1% and 66.0% sensitivity and specificity, respectively, for in-hospital mortality.

Combination tiotropium + formoterol superior to tiotropium alone in COPD patients

As reported in Pulmonary Pharmacology & Therapeutics, combination tiotropium (18 mcg) + formoterol (12 mcg) was superior to tiotropium alone in COPD (n=44) patients inadequately controlled with bronchodilator monotherapy. Combination therapy resulted in an increased bronchodilator response (FEV1 and FVC) and a maximum change in FEV1 and FVC over 24 h.

Triple therapy superior to dual therapy in HCV

As reported in Mayo Clinic Proceedings, treatment of hepatitis C virus-infected patients with triple therapy (pegylated-interferon, ribavirin, and teleprevir) is more effective than dual therapy (pegylated-interferon and ribavirin). Specifically, a sustained virologic response was achieved in 51% of treatment-naïve patients, 67% of patients with a prior non-response and 56% of patients with a prior relapse of patients treated with triple therapy compared to 37%, 11%, and 27% of patients treated with dual therapy, respectively.

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Clinical Pearl from Smartest DocDie FDG-PET stellt bei Patienten mit Melanom im Stadium III ein nützliches Hilfsmittel für die Suche nach Fernmetastasen dar.

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Clinical Pearl from Smartest DocDie Substitution von Vitamin D ist bei der Prävention der Herzinsuffizienz unwirksam.

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