Effects of EG-VEGF, VEGF and TGF-1 on pregnancy outcome in patients undergoing IVF-ET treatment.
Journal of Assisted Reproduction and Genetics, 08/03/2012
Gao Mz et al. – This study investigates the correlation of endocrine gland–derived vascular endothelial growth factor (EG–VEGF), vascular endothelial growth factor (VEGF) and transforming growth factor beta 1 (TGF–?1) with the corresponding reproductive outcome in patients who received in vitro fertilization–embryo transfer (IVF–ET).It was found that both concentrations of EG–VEGF and VEGF in FF were negatively correlated with ovarian response and oocyte maturation. Concentrations of all the three growth factors in serum were positively correlated with embryo quality, but only serum concentrations of EG–VEGF were associated with the pregnancy outcome.