Effects of parity and gestational age on second-trimester induction–abortion interval in combination with osmotic dilators and gemeprost
Contraception, 08/01/2012
Clinical Article
Kai K et al. – In combination with osmotic dilators and gemeprost, gestational age and parity are independent factors that affected the induction to abortion interval of second–trimester medical abortion.
Methods- Authors studied 216 consecutive women.
- Pregnancy was terminated with cervical preparation using osmotic dilators followed by 1 mg vaginal gemeprost administered every 3 h for a maximum of five doses in the first 24 h.
- All variables are expressed in categorical form (parity, gestational age, maternal age and body mass index) and analyzed by the Cox proportional hazards model.
- Parity 7ge;3 was associated with a shorter duration of the induction–abortion interval (adjusted hazards ratio 1.96; 95% confidence interval 1.13–3.40).
- A gestational age ≥16 weeks was associated with a longer duration of the induction–abortion interval (0.71; 0.52–0.98).
- No significant association was found in maternal age and body mass index.
