Long-Term Effect of Infection Prevention Practices and Case Mix on Cesarean Surgical Site Infections.
Obstetrics and Gynecology, 07/31/2012
Kittur, Nupur D et al. – This study was done with the aim to estimate trends in patient characteristics and obstetric complications in an 8–year cohort of patients undergoing cesarean delivery and to use time series analysis to estimate the effect of infection prevention interventions and secular trends in patient characteristics on postcesarean delivery surgical site infections. It was seen that over the study period, there was a significant increase in the proportion of patients who underwent cesarean delivery who had BMIs of 35 or higher, hypertension or mild preeclampsia, and severe preeclampsia or eclampsia.A change in policy to administer prophylactic antibiotics before incision resulted in a 48% reduction in cesarean delivery surgical site infections.