The relationship between pregnancy and oxidative stress markers on patients undergoing ovarian stimulations.
Journal of Assisted Reproduction and Genetics, 08/01/2012
Younis A et al. – This study investigated the activities and relevance of a validated panel of antioxidant enzymes, cytokines, specific lipid peroxidation end products and six fatty acids by correlational analyses with peak E2 levels and pregnancy outcome after ovarian stimulation for IVF or IUI.It was seen that ovarian stimulation causes a significant increase in serum PON1, SOD, GPx and IL–6 activity in women undergoing IVF or IUI. The high levels of IL–6, SOD, and PON1 and lower levels of palmitic, and stearic acids in the pregnancy positive group indicate that these oxidative stress and nutritional factors may be used as a predictive marker in controlled ovarian stimulation success.