The serotonin 1A receptor gene confer susceptibility to mood disorders: results from an extended meta-analysis of patients with major depression and bipolar disorder
European Archives of Psychiatry and Clinical Neuroscience, 07/06/2012
Evidence Based Medicine
Kishi T et al. – Results from this expanded meta–analysis, which included the authors' own new study, suggest that rs6295 and rs878567 in HTR1A are related to the pathophysiology of mood disorders (MDs), with overlap between major depressive disorder and bipolar disorder. Findings provide additional clues to the underlying biology and treatment targets in MDs.