Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
The Journal of Allergy and Clinical Immunology,
Chipps BE et al. – Recent exacerbation history was the strongest predictor of future asthma exacerbations. Uncontrolled asthma, as defined by the 2007 National Heart, Lung, and Blood Institute guidelines' impairment domain, was highly prevalent and predictive of future asthma exacerbations; this assessment can be used to identify high–risk patients. IgE and allergen sensitization played a role in the majority of severe or difficult–to–treat asthmatic patients.