Amino-Terminal Extended Peptide Single-Chain Trimers Are Potent Synthetic Agonists for Memory Human CD8+ T Cells
The Journal of Immunology, 06/15/2012
Carreno BM et al. – The findings demonstrate that modified peptide–MHC structures, such as amino–terminal extended peptide MHC class I single–chain trimer (AT–SCT), can be engineered as T cell agonists to promote the growth and expansion of memory human CD8+ T cells.



