Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells
The Journal of Immunology, 05/24/2012
Hagness M et al. – The authors examined the effect of a set of signaling inhibitors that perturb effector T cell activation and found that none of the examined inhibitors affected Treg activation, indicating pathway redundancy or that Treg activation proceeds by signaling mechanisms distinct from those of effector T cells.



