Successful Treatment of Brainstem Blastomycosis with Fluconazole

Clinical Medicine & Research, 05/17/2012

The lipid formulation of amphotericin B is the initial drug of choice for central nervous system blastomycosis, but it is costly and associated with significant toxicity. This case report details a patient with primary pulmonary blastomycosis with dissemination to the skin, one joint, and the brainstem that was successfully treated solely with high–dose fluconazole.

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