Markers of the APC/β-Catenin Signaling Pathway as Potential Treatable, Preneoplastic Biomarkers of Risk for Colorectal Neoplasms
Cancer Epidemiology, Biomarkers & Prevention, 05/15/2012
Ahearn TU et al. – The preliminary data suggest that the combined expression of adenomatous polyposis coli (APC) and β–catenin in the normal rectal mucosa may be associated with risk for incident, sporadic colorectal neoplasms, as well as with modifiable risk factors for colorectal neoplasms. The results may help advance the development of treatable, preneoplastic biomarkers of risk for colorectal neoplasms.