mdlinx mdlinx
Latest (262) Full Text Articles (5432) Focus on Heart Failure Article Summary

Statins after recent stroke reduces recurrence and improves survival in an aging Mediterranean population without known coronary heart disease
Journal of Clinical Pharmacy and Therapeutics,  Clinical Article

Sicras–Mainar A et al. – Statin therapy in patients with first–ever acute stroke lowers the risk of 6–year stroke recurrence and improves survival in an aging Mediterranean cohort. These results add additional evidence in routine clinical practice to the observed effects of statins in clinical trials.

Methods
  • A retrospective study was carried out using records on death, hospitalizations owing to stroke and history of statin therapy included in the Badalona Serveis Assistencials (BSA) database.
  • The cohort studied consisted of consecutive patients covered by the BSA health provider plan with a first–ever acute stroke episode during January 2003 until December 2008, for whom there was available information covering the 6–year follow–up period.
  • Recurrence rate (RR) and incidence rate (IR) of fatal/non–fatal stroke and all–causes mortality were computed.
  • Association with statin therapy was assessed by means of calculation of relative risk (RR) and hazard ratio (HR) using multivariate logistic regression and Cox proportional hazards models controlling for confounding covariates.

Results
  • The cohort comprised a series of 601 consecutive patients [57% men, 75•9 (12•4) years old (88% >60 years)].
  • Of these, 32% received statins, which were associated with lower fatal/non–fatal recurrent stroke RR; 7% vs. 18% [adjusted RR = 0•32 (CI: 0•16–0•61), P = 0•001] and lower IR; 16•78 vs. 45•22 events/year–1000 subjects [adjusted HR = 0•35 (0•19–0•64), P = 0•001].
  • Similarly, observed all–causes mortality was lower in the cohort receiving statins; 11% vs. 16% [adjusted RR = 0•29 (CI: 0•08–1•12), P = 0•072], and also mortality rate; 26•09 vs. 36•25 deaths/year–1000 subjects [adjusted HR = 0•23 (0•08–0•67), P = 0•007].

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Family Medicine

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Family Medicine Articles

Last month's top read Top Articles of 2013

1 Coffee consumption and prostate cancer risk: An updated meta-analysis Cancer Causes and Control, March 3, 2014    Evidence Based Medicine    Clinical Article

2 Coffee intake and gastric cancer risk Cancer Epidemiology, Biomarkers & Prevention, March 10, 2014    Clinical Article

3 Tea consumption and the risk of five major cancers: A dose-response meta-analysis of prospective studies Full Text BMC Cancer, March 18, 2014    Free full text    Evidence Based Medicine    Review Article

4 Coffee intake and gastric cancer risk Cancer Epidemiology, Biomarkers & Prevention, March 19, 2014    Clinical Article

5 Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial Complementary Therapies in Medicine, March 4, 2014    Clinical Article

6 Associations between serum 25-hydroxyvitamin D concentrations and multiple health conditions, physical performance measures, disability, and all-cause mortality: The Concord Health and Ageing in Men Project Journal of the American Geriatrics Society, March 13, 2014    Clinical Article

7 Egg consumption and cardiovascular disease among diabetic individuals: A systematic review of the literature Full Text Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, March 28, 2014    Free full text    Review Article

8 Effects of pomegranate juice consumption on inflammatory markers in patients with type 2 diabetes: A randomized, placebo-controlled trial Journal of Research in Medical Sciences, March 20, 2014    Clinical Article

9 Effects of yoga on cardiovascular disease risk factors: A systematic review and meta-analysis International Journal of Cardiology, March 17, 2014    Evidence Based Medicine    Review Article    Clinical Article

10 Effect of omega-3 fatty acid supplementation on cancer incidence, non-vascular death, and total mortality: a meta-analysis of randomized controlled trials Full Text BMC Public Health, March 5, 2014    Free full text    Evidence Based Medicine    Clinical Article

11 The effect of green tea on blood pressure and lipid profile: A systematic review and meta-analysis of randomized clinical trials Nutrition, Metabolism & Cardiovascular Diseases, March 27, 2014    Evidence Based Medicine    Review Article

12 The effect of three weeks green tea extract consumption on blood pressure, heart rate responses to a single bout resistance exercise in hypertensive women High Blood Pressure & Cardiovascular Prevention, March 14, 2014    Clinical Article

13 Meat consumption and the risk of hepatocellular carcinoma Alimentary Pharmacology and Therapeutics, March 6, 2014    Review Article

14 Tea consumption and leukemia risk: A meta-analysis Tumor Biology, February 12, 2014    Evidence Based Medicine    Clinical Article

15 Is breakfast skipping associated with physical activity among US adolescents? A cross-sectional study of adolescents aged 12–19 years, National Health and Nutrition Examination Survey (NHANES) Public Health Nutrition, March 12, 2014    Clinical Article

16 Dietary carrot consumption and the risk of prostate cancer European Journal of Nutrition, February 17, 2014    Clinical Article

17 The association between caffeine and cognitive decline: Examining alternative causal hypotheses International Psychogeriatrics, March 18, 2014    Review Article

18 Estimation of fish intake in Asian and white female adolescents, and association with 2-year changes in body fatness and body fat distribution: The Female Adolescent Maturation Study Journal of the Academy of Nutrition and Dietetics, March 24, 2014    Clinical Article

19 The low-carbohydrate diet and cardiovascular risk factors: Evidence from epidemiologic studies Nutrition, Metabolism & Cardiovascular Diseases, March 12, 2014    Evidence Based Medicine    Review Article

20 A green and black tea extract benefits urological health in men with lower urinary tract symptoms Therapeutic Advances in Urology, March 26, 2014    Clinical Article

Indexed Journals in Family Medicine: American Family Physician, Archives of Family Med, Annals of Family Medmore

Other Topics in Family Medicine

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Stay current - Media Tool

Newsletter
RSS
Follow
Like

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close