Mapping the cytokine profile of painful bladder syndrome/interstitial cystitis in human bladder and urine specimens

World Journal of Urology, 03/30/2012

The results indicate significant elevation of cytokines in painful bladder syndrome/interstitial cystitis (PBS/IC) bladder tissue relative to controls. Significant reduction in post–hydrodistention (HD) urine levels of MCP–3 and TRAIL relative to pre–HD in PBS/IC was associated with clinical improvement to qualify them as biomarker candidates.

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