Effects of red ginseng extract on sleeping behaviors in human volunteers

Journal of Ethnopharmacology , 08/08/2013

Han HJ et al. – This study was performed to investigate how red ginseng extract (RGE) affects sleeping behaviors in human volunteers. From these results, it is presumed that RGE intake would improve the quality of sleep, thus having beneficial effects on sleep disturbed subjects.


  • RGE (1500 mg) was orally administered to young male healthy volunteers (from 15 to 37 years old ages, n=15) three times a day for 7 days.
  • Overnight polysomnographic (PSG) studies were performed two times, 1 day before and 7 days after RGE administration.
  • The authors investigated differences in sleep architecture parameters such as total sleep time (TST), sleep efficacy (SE: total sleep time/time in bed), proportion of each sleep stage, and wakefulness after sleep onset (WASO) between baseline PSG and PSG after RGE administration.


  • Total wake time (TWT) was significantly reduced (P<0.05) and SE was increased (P<0.05), although slow wave sleep stage 1 (N1) was reduced (P<0.01) and non-rapid eye movement (REM) sleep was increased (P<0.03) after administration.

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