Treat gout with anti-inflammatories and urate-lowering therapies, unless such treatment is ineffective or inappropriate

Drugs & Therapy Perspectives, 05/16/2012

Current standard treatments are ineffective, poorly tolerated or inappropriate in some patients, which had promoted the development of new therapies.

  • Gout is caused by chronic hyperuricaemia and the formation of pro–inflammatory monosodium urate crystals in the joints.
  • Pain associated with acute gout flares is treated with anti–inflammatories (e.g. NSAIDs, colchicine and corticosteroids).
  • Chronic gout is managed with urate–lowering therapies (e.g. xanthine oxidase inhibitors).

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