Angiogenesis related gene expression profiles of EA.hy926 cells induced by irbesartan: a possible novel therapeutic approach
Chinese Medical Journal, 05/08/2012Cong M et al.
The study showed that irbesartan may induce angiogenic effects in vascular endothelial cells. It suggested that the mechanism of angiogenic effects of Angiotensin II type 1 receptor blockers might be attributed to the signaling cascade from angiotensin receptors in the VEGF pathway. It also provided evidence indicating that Angiotensin II type 1 receptor blockers could be used as a novel therapeutic approach to treat chronic ischemic heart disease as well as anti–hypertensive agents.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.