Prevalence of Noncalcified Coronary Plaque in Patients With Calcium Score of 0: The Silent Enemy
Koulaouzidis G et al. - Computer tomography coronary angiography could be of diagnostic value in symptomatic patients with multiple risk factors for coronary artery disease (CAD), even in the absence of CAC.
The authors evaluated the prevalence and degree of stenosis caused by NCAP in patients without coronary artery calcification (CAC).
A retrospective analysis of 447 symptomatic patients with 0 CAC score revealed negative CTCA in 400 (89.5%). Noncalcified coronary artery plaques were demonstrated in 47 (10.5%), with 4 presenting stenosis >50%.
Patients with positive CTCA, compared to those with normal CTCA, had significantly higher mean age (56.2 years vs 50.6 years, P < .004) and higher pretest coronary artery disease (CAD) probability (26% vs 34%, P < .0001).
Noncalcified coronary artery plaque was predominantly developed in the proximal segment of the left anterior descending artery.
Noncalcified coronary artery plaque is present in up to 10% of patients with a CAC score of 0.
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