Low vitamin D levels, prediabetes and prehypertension in healthy African American adults
Nutrition, Metabolism & Cardiovascular Diseases, 04/13/2012Gupta AK et al.
Evaluating serum vitamin D levels, with consideration for supplementation in seemingly healthy african american (AA) adults with prediabetes, prehypertension, or co–existing prediabetes and prehypertension, has merit.
Disease free AA adults in the National Health and Nutrition Examination Survey 2001–2006 were assessed.
PreDM and PreHTN were diagnosed using the ADA and JNC 7 criteria: (FPG) 100–125 mg/dL and resting systolic (SBP) 120–139 and/or diastolic (DBP) 80–89 mm Hg, respectively.
Logistic regression was employed to assess effects of low vitamin D concentrations on the odds for PreDM and PreHTN (n = 621).
Age, gender and BMI adjusted odds ratio for co–morbid PreDM and PreHTN in AA men (n = 343) and women (n = 278) with vitamin D levels ≤45.4 versus >45.4 nmol/L was 2.02 (1.11, 3.68), (p < 0.021).
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