Low vitamin D levels, prediabetes and prehypertension in healthy African American adults

Nutrition, Metabolism & Cardiovascular Diseases, 04/13/2012

Evaluating serum vitamin D levels, with consideration for supplementation in seemingly healthy african american (AA) adults with prediabetes, prehypertension, or co–existing prediabetes and prehypertension, has merit.

Methods

  • Disease free AA adults in the National Health and Nutrition Examination Survey 2001–2006 were assessed.
  • PreDM and PreHTN were diagnosed using the ADA and JNC 7 criteria: (FPG) 100–125 mg/dL and resting systolic (SBP) 120–139 and/or diastolic (DBP) 80–89 mm Hg, respectively.

Results

  • Logistic regression was employed to assess effects of low vitamin D concentrations on the odds for PreDM and PreHTN (n = 621).
  • Age, gender and BMI adjusted odds ratio for co–morbid PreDM and PreHTN in AA men (n = 343) and women (n = 278) with vitamin D levels ≤45.4 versus >45.4 nmol/L was 2.02 (1.11, 3.68), (p < 0.021).

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