Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
American Journal of Clinical Nutrition, 03/08/2012
Wedick NM et al. – A higher consumption of anthocyanins and anthocyanin–rich fruit was associated with a lower risk of type 2 diabetes.
The authors followed up a total of 70,359 women in the Nurses’ Health Study (NHS; 1984–2008), 89,201 women in the NHS II (1991–2007), and 41,334 men in the Health Professionals Follow–Up Study (1986–2006) who were free of diabetes, cardiovascular disease, and cancer at baseline.
During 3,645,585 person–years of follow–up, they documented 12,611 incident cases of type 2 diabetes.
Higher intakes of anthocyanins were significantly associated with a lower risk of type 2 diabetes (pooled HR for the 3 cohorts from a comparison of extreme quintiles: 0.85; 95% CI: 0.80, 0.91; P–trend < 0.001) after multivariate adjustment for age, BMI, and lifestyle and dietary factors.
Consumption of anthocyanin–rich foods, particularly blueberries and apples/pears was also associated with a lower risk of type 2 diabetes.
No significant associations were found for total flavonoid intake or other flavonoid subclasses.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.