Tobacco and alcohol use significantly increase risk for ESCC
Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.
Green tea reduces BP and improves lipid profile
As reported in Nutrition, Metabolism, and Cardiovascular Diseases, a meta-analysis involved 20 RCTs and 1536 participants showed that consumption of green tea (Camellia sinensis) is associated with a reduction in systolic blood pressure (-1.94 mmHg) and improved lipid profile (TC, -0.13 mmol/l; LDL-C, -0.19 mmol/l). Additional studies quantifying the association are needed.
Belimumab safe and effective in childhood-onset SLE
As reported in Arthritis and Rheumatology, belimumab (a human monoclonal antibody targeting soluble B-lymphocyte stimulator) is effective and well-tolerated in children with SLE (n=7). The mean follow-up was 9.3 months. The SLEDAI decreased from 6.4 to 4 and 57% of recipients were able to taper steroids. Clinical response was evident by 3 months.