We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Differential post-prostatectomy cancer-specific survival of occult T3 vs. clinical T3 prostate cancer: Implications for managing patients upstaged on prostate magnetic resonance imagingUrologic Oncology: Seminars and Original Investigations, May 22, 2015  Clinical Article
2Metastasis initiating cells in primary prostate cancer tissues from transurethral resection of the prostate (TURP) predicts castration-resistant progression and survival of prostate cancer patientsThe Prostate, May 22, 2015  Clinical Article
3Is whole gland salvage cryotherapy effective as palliative treatment of haematuria in patients with locally advanced prostate cancer? Results of a preliminary case seriesTherapeutic Advances in Urology, May 22, 2015  Clinical Article
4EAU guidelines on the assessment of non-neurogenic male lower urinary tract symptoms including benign prostatic obstructionEuropean Urology, May 22, 2015  Full Text
5High dose versus conventional dose in external beam radiotherapy of prostate cancer: A meta-analysis of long-term follow-upJournal of Cancer Research & Clinical Oncology, May 22, 2015  Clinical Article
6Utilization of surgical procedures and racial disparity in the treatment of urinary incontinence after prostatectomyNeurourology and Urodynamics, May 22, 2015  Evidence Based Medicine  Review Article
7The association between neuroticism and heart rate variability is not fully explained by cardiovascular disease and depressionPLOS ONE, May 22, 2015  Clinical Article
8Efficacy of duloxetine in the early management of urinary continence after radical prostatectomyCurrent Urology, May 22, 2015  Clinical Article
9Accuracy of cognitive MRI-targeted biopsy in hitting prostate cancer-positive regions of interestWorld Journal of Urology, May 22, 2015  Clinical Article
10Systematic review and meta-analysis of factors determining change to radical treatment in active surveillance for localized prostate cancerEuropean Urology, May 22, 2015  Full Text  Evidence Based Medicine  Review Article

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We have Ranked, Sorted and Summarized the Latest Clinical Articles.

1Smokers don't vote: 11,626-person study shows marginalization of tobacco usersUniversity of Colorado Health News, May 22, 2015
2Oral steroids for acute sciatica produce limited improvement in function and painKaiser Permanente Health Research News, May 22, 2015
3Maternal obesity compromises babies’ immune system at time of birthThe University of California, Riverside Health News, May 22, 2015
4Drinking chamomile decreases risk of death in older Mexican American womenUniversity of Texas Medical Branch at Galveston, May 22, 2015
5Growing up with smokers doubles smoking risk for adult HispanicsUniversity of Illinois at Chicago Health News, May 22, 2015
6Home-brewed opiates serious public health concernUniversity of Alberta Faculty of Medicine & Dentistry News, May 22, 2015
7Risk of sudden deafness shown to be higher in people with osteoporosisInternational Osteoporosis Foundation News, May 22, 2015
8Rollins researchers develop prenatal vaccination resource websiteEmory's Woodruff Health Sciences Center News, May 22, 2015
9When it comes to hearing, diet may trump noise exposureUF Health, May 22, 2015
10U-M allergist: News on asthma and peanut allergies in kids could lead to misdiagnosis, unnecessary testingUniversity of Michigan Health System, May 22, 2015

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Tobacco and alcohol use significantly increase risk for ESCC

Based on a meta-analysis (n=5 studies) reported in the American Journal of Gastroenterology, the combined use of tobacco and alcohol increased the risk for esophageal squamous cell carcinoma (OR=3.28) compared with non-users; users of tobacco or alcohol alone had a 20%-30% increased risk of esophageal squamous cell carcinoma compared to non-users.

s-H-FABP levels predict outcome in ICU patients

As reported in Clinical Research in Cardiology, the level of serum heart-type fatty acid-binding protein (s-H-FABP) is higher in ER patients admitted to the ICU than ER patients admitted to other departments. The s-H-FABP level was also higher in ICU non-survivors than ICU survivors. A s-H-FABP level of 20.95 ng/ml had a 81.1% and 66.0% sensitivity and specificity, respectively, for in-hospital mortality.

Triple therapy superior to dual therapy in HCV

As reported in Mayo Clinic Proceedings, treatment of hepatitis C virus-infected patients with triple therapy (pegylated-interferon, ribavirin, and teleprevir) is more effective than dual therapy (pegylated-interferon and ribavirin). Specifically, a sustained virologic response was achieved in 51% of treatment-naïve patients, 67% of patients with a prior non-response and 56% of patients with a prior relapse of patients treated with triple therapy compared to 37%, 11%, and 27% of patients treated with dual therapy, respectively.

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Clinical Pearl from Smartest DocNicotine use is a gateway drug to marijuana and cocaine.

Clinical Pearl from Smartest DocCompared to never smokers, smokers of >15 cigarettes per day can have a 42% increased risk of cataract extraction.

Clinical Pearl from Smartest DocPentoxifylline plus RAS blockade can slow the progression of renal disease in patients with type 2 diabetes.

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