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Low pH-Triggered Beta-Propeller Switch of the Low-Density Lipoprotein Receptor Assists Rhinovirus Infection
Journal of Virology, 10/12/09
Konecsni T et al. – The data indicate that the beta–propeller attenuates the virus–stabilizing effect of LDLR binding and thereby facilitates RNA release from endosomes, resulting in the enhancement of infection. This is a nice example of a virus exploiting high–avidity multimodule receptor binding with an intrinsic release mechanism.
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