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Adverse effects of Sudanese toombak vs. Swedish snuff on human oral cells
Journal of Oral Pathology and Medicine, 10/06/09
Costea DE et al. – This study indicates a potential for toombak, higher than for Swedish snuff, to damage human oral epithelium. Dysplastic oral keratinocytes were less sensitive than their normal counterparts, suggesting that they might have acquired a partially resistant phenotype to toombak–induced cytotoxic effects while still being prone to DNA damage that could lead to further malignant progression.
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