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Dissolution in nasal fluid, retention and anti-inflammatory activity of fluticasone furoate in human nasal tissue ex vivo
Clinical and Experimental Allergy, 09/25/09

Baumann D et al. – FF displayed beneficial properties for nasal application. Its low application volume per spray is a prerequisite for effective drug utilization by avoiding immediate loss by nose runoff or drip down the throat. Sustained dissolution and high tissue binding of FF should contribute towards an extended presence of compounds in nasal tissue as a basis for a prolonged pharmacologic activity.

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Effect of Fluticasone With and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Annals of Internal Medicine, 10/20/09 Relevance Score: 92%

Parasternal muscle activity decreases in severe COPD with salmeterol-fluticasone propionate
Chest, 10/20/09 Relevance Score: 84%

Mometasone furoate vs fluticasone propionate with salmeterol: multivariate analysis of resource use and asthma-related charges
Current Medical Research and Opinion, 10/19/09 Relevance Score: 80%

Add-on salmeterol compared to double dose fluticasone in pediatric asthma: A double-blind, randomized trial (VIAPAED)
Pediatric Pulmonology, 10/14/09 Relevance Score: 80%

Effect of Fluticasone Propionate/Salmeterol (250/50) on COPD Exacerbations and Impact on Patient Outcomes
COPD: Journal of Chronic Obstructive Pulmonary Disease, 10/06/09 Relevance Score: 80%