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Immunohistochemical analysis of P53 and bcl-2 in benign and malignant salivary glands tumors
Journal of Oral Pathology and Medicine, 09/17/09
AL–Rawi et al. – All malignant tumors expressed P53, with the highest record in low–grade adenocarcinoma and the lowest score was observed in both low–grade carcinoma in PA and adenocystic carcinoma. bcl–2 immunostaining was also assessed, the highest recorded score was in high–grade adeno cystic carcinoma and the lowest in both low–grade carcinoma ex–PA and low–grade cystic mucoepidermoid carcinoma. P53/bcl–2 immunostaining reactivity could be helpful in demonstrating salivary glands tumor behavior in terms of progression and extent of invasion.
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