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Transforming growth factor-beta receptor type 1 (TGFBR1) is not associated with non-syndromic cleft lip with or without cleft palate in patients of Central European descent
International Journal of Pediatric Otorhinolaryngology , 09/11/09
Reutter H et al. – Despite the ample evidence supporting the role of TGF–beta type 1 receptor as a critically important and widespread morphogenetic regulator of craniofacial development in murine models, the results do not support TGFBR1 as major risk factor for NSCL/P in patients of Central European descent.
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