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Indicators for the correct usage of intranasal medications: A computational fluid dynamics study
The Laryngoscope, 08/06/09

Garlapati RR et al. – When using an intranasal medication, it is advisable to have an inspiratory flow to improve drug penetration. Various suggested head positions do not improve drug penetration significantly, even in the presence of uniform quiet breathing. Further studies that consider turbulence and unsteady airflow are needed to investigate the deposition distribution of discrete particles inside various nasal cavities.

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