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Acha–Sagredo A et al. – The aim of the study was to determine the status of the tumour suppressor gene p53 in the oral mucosa of patients previously treated for a head and neck squamous cell carcinoma, at risk of developing an oral squamous cell carcinoma, but without oral clinical lesions. Mutation of the tumour suppressor gene p53 does not seem to be a frequent event in patients at risk but without oral lesions.


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