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Differential expression of galectin-3, beta-catenin, and cyclin D1 in adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma of salivary glands
Journal of Oral Pathology and Medicine, 08/10/09

Ferrazzo KL et al. – The results suggest that in ACC galectin–3 may play a role in cellular proliferation through cyclin D1 activation. In addition, nuclear expression of galectin–3 in ACC may be related to a more aggressive behavior of this lesion. Although beta–catenin seems to play a role in carcinogenesis in both lesions, it seems that it does not bind to galectin–3 for cyclin D1 stimulation.

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