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Oral verrucous hyperplasia: histologic classification, prognosis, and clinical implications
Journal of Oral Pathology and Medicine, 07/28/09
Wang YP et al. – The authors conclude that OVH lesions occur more commonly on the buccal mucosa and are highly associated with the areca quid chewing and cigarette smoking habits. The overall 5–year malignant transformation rate of 60 OVH lesions was 10%. The mass–typed OVH lesions had a higher malignant transformation rate than the plaque–typed OVH lesions and thus should receive an immediate treatment, such as total surgical excision or photodynamic therapy, after the histopathologic diagnosis.
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