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Lingyong J et al. – Recently, with the study of calcium in polarity of cells or tissues, it was found that calcium can regulate the polarity of cells or tissues. Deficiency of calcium which may bring about the loss of polarity, could be a new pathogenesis of aphthous ulcer, meanwhile, supplement of calcium is necessary for gestation in order to avoid not only occurrence of osteoporosis and hypertension, but also prevention of aphthous ulcer and healing of focus.

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