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In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment
Human Molecular Genetics, 07/28/09
Morín M et al. – The results provide a more complete picture of the biological consequences of deafness–associated gamma–actin mutants and support the hypothesis that the post–lingual and progressive nature of the DFNA20/26 hearing loss is the result of a progressive deterioration of the hair cell cytoskeleton over time.
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