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Haerle SK et al. – 18F–FDG–PET/CT is superior to panendoscopy. With a negative 18F–FDG–PET/CT, the extent of endoscopy can be reduced to the area of the primary tumor. Due to the costs, 18F–FDG–PET/CT is recommended only in advanced disease to assess potential distant disease. In early–stage cancer, panendoscopy is accurate enough to rule out secondary tumors.

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