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Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese
Journal of Allergy and Clinical Immunology, 07/28/09
Cao PP et al. – Both Chinese CRSsNP and CRSwNP patients demonstrate impaired regulatory T cell function and enhanced TH1/TH2/TH17 responses. CRSsNP is confirmed to be a predominant TH1 milieu, whereas TH2 skewed inflammation with predominant TH17 reactions, and infiltration of natural killer T cells can be demonstrated only in eosinophilic CRSwNP, but not in noneosinophilic CRSwNP.
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