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See Latest ArticlesLow COX2 in tumor and upregulation in stroma mark laryngeal squamous cell carcinoma progression
The Laryngoscope, 06/26/09
Kourelis K et al. - In laryngeal SCCs, COX-2 may exert its deleterious effect by alterations in the tumor microenvironment. CAF-derived, COX-2-mediated paracrine influences on malignant cells possibly facilitate cancer progression. Overlooking the stromal remodeling could account for unsuccessful treatments of epithelial neoplasms.
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