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CT assessment of woodworkers' nasal adenocarcinomas confirms the origin in the olfactory cleft
American Journal of Neuroradiology, 06/19/09

Georgel T et al. - Study suggests that radiologists should suspect nasal adenocarcinoma on sinus CT scans showing a unilateral expanding opacity of the olfactory cavity.

Methods

Aim was to identify the CT imaging features that corroborate the olfactory cleft as the site of origin for woodworkers' adenocarcinoma
CT scans of 27 unilateral olfactory cleft adenocarcinomas were compared with 30 cases of nasosinusal polyposis (NSP) and 33 healthy sinus controls
Enlargement of the olfactory cleft, lateralization of the ethmoidal turbinate wall, and contralateral bulging of the nasal septum were measured on coronal scans passing through crista galli and posterior half of both ocular globes

Results

Nasal septum was bulging across the midline in adenocarcinoma vs NSP or healthy sinus controls
The olfactory cleft was significantly wider in adenocarcinoma than in NSP or healthy sinus controls
Ethmoidal labyrinth width was smaller on the pathologic side in adenocarcinoma than in control groups
Angle between the conchal lamina and vertical midline was close to zero degrees in NSP and in healthy sinus controls
It reached 39.76 ± 13.83° in adenocarcinoma

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