ENT Medical News about buccal mucosa

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Prognostic importance of site in squamous cell carcinoma of the buccal mucosa
British Journal of Oral & Maxillofacial Surgery, 06/15/09

Shaw RJ et al. - In a trial to determine the effect of site on prognosis of oral cancer, it was concluded that site had little influence on prognosis, and that the poor outcome of buccal cancers reported from other centres was not replicated in this series.

Methods

482 consecutive pts with oral cancers that had been operated on in a single unit were examined.
Presentation, treatment, and outcome were reported of buccal tumours compared with those of other oral sites with reference to other prognostic variables.

Results

There were no significant differences between buccal and other cancers in pts’ characteristics, clinical presentation, or pathological staging, except in buccal tumours that rarely had pT1 stage (n=13, 16%) compared with other sites (n=112, 28%, pT1-4).
Despite a higher rate of frankly involved margins, 5-yr disease-specific survival was 70% for buccal tumours vs 75% for other sites.

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