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Enhancement of Odorant-Induced Responses in Olfactory Receptor Neurons by Zinc Nanoparticles
Chemical Senses, 06/22/09
Vodyanoy V et al. - The authors hypothesize that zinc nanoparticles are closely located to the interface between the guanine nucleotide-binding protein and the receptor proteins and are involved in transferring signals in the initial events of olfaction. The authors' results suggest that zinc metal nanoparticles can be used to enhance and sustain the initial olfactory events.
Vitaly Vodyanoy, 06/22/09
| It is not a surprise that zinc is important for olfaction. Real news for us is a physical state of zinc. It is zinc metal nanoparticles and not zinc ions are very important for the sense of smell. There is a significant difference between zinc ions and zinc nanoparticles. A zinc ion is a single atom that lost 2 electrons to make it positively charged. The metal zinc nanoparticle is comprised of a relatively large number of neutral atoms. For example, 1-nm zinc nanoparticles contain ~40 atoms, but 2-nm particle has ~300 atoms. Where we are getting these wonderful particles? There is no surprise again: from fresh fruits and vegetables. |
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