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Murphy TF et al. - Moraxella catarrhalis is an exclusively human pathogen and is a common cause of otitis media in infants and children, causing 15%–20% of acute otitis media episodes. M. catarrhalis causes an estimated 2–4 million exacerbations of chronic obstructive pulmonary disease in adults annually in the United States. Recent work has elucidated mechanisms of pathogenesis and focused on vaccine development to prevent otitis media in children and respiratory tract infections caused by M. catarrhalis in adults with chronic obstructive pulmonary disease.


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