ENT Medical News about Hypothyroidism

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Hypothyroidism in postradiation head and neck cancer patients: Incidence, complications, and management
Current Opinion in Otolaryngology and Head & Neck Surgery, 05/01/09

Miller MC et al. - Hypothyroidism is common after treatment of head and neck cancers. Therefore the thyroid function studies should be obtained prior to and at regular intervals after treatment. Prompt recognition and intervention may prevent or reverse adverse physiological outcomes.

Methods

A review to describe the incidence, risk factors, prevention, and management of hypothyroidism among pts treated with radiation and other modalities for head and neck cancers

Results

Hypothyroidism may occur in up to 48% of pts treated for head and neck malignancies
It has been observed after radiation, surgery, and combined-modality therapies
The onset of hypothyroidism ranges from 4 wks to 5 or 10 yrs after completion of therapy
It is associated with poor wound healing, bleeding disorders, and a number of other potential complications
There is some evidence to suggest a protective role of hypothyroidism with respect to disease control survival in head and neck and other cancers

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