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Multiple Viral Genome Search in Endolabyrinthic Fluids of Profoundly Deaf Patients: Possible Cytomegalovirus Intracochlear Reactivation
Audiology & Neuro-Otology, 04/23/09
Nardo WD et al. - The finding of CMV genome within the cochlea of a deaf patient without any evidence of acute and prenatal CMV infection suggests its possible role in postnatal inner ear injury through reactivation of latent virus within the cochlea. This hypothesis could also be considered valid for some patients with anti-CMV-IgG-positive serology and absence of endolabyrinthine viral genome since viruses can be in an inactive state at the time of fluid collection.
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