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Reflux changes in adenoidal hyperplasia: a controlled prospective study to investigate its aetiology
Clinical Otolaryngology, 04/09/09
Harris PK et al. - The results suggest that the biochemical changes seen in adenoid hypertrophy are different to those seen in reflux-affected tissues. The decreased COX-2 and MUC5AC expression may be due to squamous metaplasia and other inflammatory changes associated with adenoid hypertrophy. The findings infer there is little evidence of reflux being a major contributory factor in the pathophysiology of adenoidal hypertrophy.
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