ENT Medical News about neuroendocrine carcinoma

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Small cell neuroendocrine carcinoma of nose and paranasal sinuses: a study of three cases with short review of the literature
Indian Journal of Otolaryngology and Head & Neck Surgery, 04/03/09

Chatterjee DN et al. - Primary small cell neuroendocrine carcinoma usually occurs in elderly persons with main complaints being nasal obstruction, epistaxis, loss of visual acuity, exophthalmos, local pain and rarely tender swelling over the sinuses. Computerized tomography scan is essential to assess the size, extent of the tumour, evidence of bone destruction and infiltration to orbit and brain. Due to its rarity, the understanding of pathogenesis of the disease, diagnosis and ideal treatment have been difficult. The origin of the tumour is believed from basal cells of the olfactory mucosa.

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