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Recurrent laryngeal nerve paralysis in patients with papillary thyroid carcinomas: Evaluation and management of resulting vocal dysfunction
The American Journal of Surgery, 04/02/09
Roh JL et al. – Study indicates that patients with papillary thyroid carcinomas (PTC) may have vocal dysfunction from cancer or surgery-related recurrent laryngeal nerve paralysis (RLNP). Vocal evaluation and management may help improve their vocal function, thus enhancing their quality of life.
Methods- Study to evaluate vocal function and management outcomes of pts with PTCs and RLNP
- Of 319 PTC pts:
- 256 underwent total thyroidectomy with or w/o neck dissection
- 42 underwent lobectomy
- and 21 underwent reoperation for recurrent cancers
- All pts underwent laryngoscopy and vocal function measurements before and after surgery
- Pts with RLNP and poor vocal function underwent voice surgery
- Temporary and permanent RLNP rates were 2.8% and 0.9% at nerve-at-risk–based analysis, respectively
- Of 28 pts with tumor invasion of RLN, 14 had preoperative RLNP, with 9/14 showing voice changes
- RLNP was detected in 9/291 (3.1%) pts w/o documented nerve injury; 8 recovered
- 9/15 pts with RLN section had poor vocal function, which improved in 8 pts after medialization of the unilateral vocal fold
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