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Prothrombotic Gene Mutations in Patients With Sudden Sensorineural Hearing Loss and Cardiovascular Thrombotic Disease
Annals of Otology, Rhinology & Laryngology, 03/13/09
Capaccio P et al. - The association between inherited and acquired prothrombotic factors in patients with sudden sensorineural hearing loss and thrombotic diseases in other sites suggests that a multifactorial mechanism may underlie microvascular cochlear impairment. Hematologic investigation, including MTHFR, prothrombin, platelet, and V Leiden genotyping, may help to detect patients at potential risk of recurrent hearing loss and multiple microvascular diseases, and could be usefully performed in otherwise idiopathic sudden sensorineural hearing loss.
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