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See Latest ArticlesExtracerebellar MRI—Lesions in Ataxia Telangiectasia Go Along with Deficiency of the GH/IGF-1 Axis, Markedly Reduced Body Weight, High Ataxia Scores and Advanced Age
The Cerebellum, 11/12/09
Kieslich M et al. – Central cerebral white matter affection, spinal atrophy, and extrapyramidal symptoms are more often present in patients with pronounced deficiency of the GH/IGF–1 axis accompanied by markedly reduced body weight and high ataxia scores. This may point to a major role of IGF–1 and nutritional status in neuroprotective signaling.
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