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Transfer, Analysis and Reversion of the Fibrous Dysplasia Cellular Phenotype in Human Skeletal Progenitors
Journal of Bone and Mineral Research, 11/03/09
Piersanti S et al. – The authors demonstrated that selective silencing of the mutated allele is both feasible and effective in reverting the aberrant cAMP production brought about by the constitutively active Gsalpha, and some of its effects on in vitro differentiation of skeletal progenitors.
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