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Pericardial Fat Volume Correlates With Inflammatory Markers: The Framingham Heart Study
Obesity, 11/04/09
Tadros TM et al. – Upon backward elimination, four of the biomarkers correlated positively with each fat depot: CRP, interleukin–6, MCP–1, and urinary isoprostanes. Even after adjusting for BMI, waist circumference (WC), and abdominal visceral fat, CRP and urinary isoprostanes demonstrated significant positive associations with intrathoracic fat, but not with pericardial fat. Multiple markers of inflammation and oxidative stress correlated with pericardial and intrathoracic fat volumes, extending the known association between regional adiposity and inflammation and oxidative stress.
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