Endocrinology Medical News about Obesity-related Polymorphisms

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Corpeleijn E et al. – FTO rs9939609 was not related to fat oxidation. At the same time, the results are not adjusted for multiple testing, thus none of the associations can be considered statistically significant. The results should therefore only be considered as leads to new hypotheses about effects of specific genetic polymorphisms on fasting and postprandial fat oxidation.

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TNF superfamily gene polymorphism as prognostic factor in early breast cancer
Journal of Cancer Research & Clinical Oncology, 11/10/09 Relevance Score: 46%

Interleukin-12 gene polymorphism and cervical cancer risk
American Journal of Clinical Oncology, 10/06/09 Relevance Score: 45%

Association of IL-1B genetic polymorphisms with an increased risk of opioid and alcohol dependence
Pharmacogenetics and genomics, 10/30/09 Relevance Score: 44%

EGF61A > G polymorphism as predictive marker of clinical outcome to first-line capecitabine and oxaliplatin in metastatic colorectal cancer
Annals of Oncology, 10/28/09 Relevance Score: 44%

The -283C/T polymorphism of the DNMT3B gene influences the progression of joint destruction in rheumatoid arthritis
Rheumatology International, 10/01/09 Relevance Score: 44%