Endocrinology Medical News about Thyroid Cancer

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The BRAFV600E Oncogene Induces Transforming Growth Factor beta Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer
Cancer Research, 11/02/09

Riesco–Eizaguirre G et al. – TGFbeta is overexpressed in the invasive front, whereas NIS is preferentially expressed in the central regions of the tumors, suggesting that this negative correlation between TGFbeta and NIS occurs locally inside the tumor. The study describes a novel mechanism of NIS repression in thyroid cancer and provides evidence that TGFbeta may play a key role in promoting radioiodide resistance and tumor invasion during PTC progression.

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Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
Thyroid, 10/30/09 Relevance Score: 71%

Diffuse Sclerosing Variant Is a Major Subtype of Papillary Thyroid Carcinoma in the Young
Thyroid, 11/06/09 Relevance Score: 70%

Geographical correlation between incidence of benign disease and that of cancer of the thyroid among the population of the Rhone-Alpes region of France
European Journal of Endocrinology, 10/14/09 Relevance Score: 69%

Thyroid Cancer in Systemic Lupus Erythematosus: A Case-Control Study
Journal of Clinical Endocrinology and Metabolism, 11/12/09 Relevance Score: 68%

Thyroid cancer a risk after childhood cancer
Reuters, 10/28/09 Relevance Score: 68%